94 research outputs found
Mining Object Parts from CNNs via Active Question-Answering
Given a convolutional neural network (CNN) that is pre-trained for object
classification, this paper proposes to use active question-answering to
semanticize neural patterns in conv-layers of the CNN and mine part concepts.
For each part concept, we mine neural patterns in the pre-trained CNN, which
are related to the target part, and use these patterns to construct an And-Or
graph (AOG) to represent a four-layer semantic hierarchy of the part. As an
interpretable model, the AOG associates different CNN units with different
explicit object parts. We use an active human-computer communication to
incrementally grow such an AOG on the pre-trained CNN as follows. We allow the
computer to actively identify objects, whose neural patterns cannot be
explained by the current AOG. Then, the computer asks human about the
unexplained objects, and uses the answers to automatically discover certain CNN
patterns corresponding to the missing knowledge. We incrementally grow the AOG
to encode new knowledge discovered during the active-learning process. In
experiments, our method exhibits high learning efficiency. Our method uses
about 1/6-1/3 of the part annotations for training, but achieves similar or
better part-localization performance than fast-RCNN methods.Comment: Published in CVPR 201
Dynamic Structured Illumination Microscopy with a Neural Space-time Model
Structured illumination microscopy (SIM) reconstructs a super-resolved image
from multiple raw images captured with different illumination patterns; hence,
acquisition speed is limited, making it unsuitable for dynamic scenes. We
propose a new method, Speckle Flow SIM, that uses static patterned illumination
with moving samples and models the sample motion during data capture in order
to reconstruct the dynamic scene with super-resolution. Speckle Flow SIM relies
on sample motion to capture a sequence of raw images. The spatio-temporal
relationship of the dynamic scene is modeled using a neural space-time model
with coordinate-based multi-layer perceptrons (MLPs), and the motion dynamics
and the super-resolved scene are jointly recovered. We validate Speckle Flow
SIM for coherent imaging in simulation and build a simple, inexpensive
experimental setup with off-the-shelf components. We demonstrate that Speckle
Flow SIM can reconstruct a dynamic scene with deformable motion and 1.88x the
diffraction-limited resolution in experiment
Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components
<p>Abstract</p> <p>Background</p> <p><it>Lychas mucronatus </it>is one scorpion species widely distributed in Southeast Asia and southern China. Anything is hardly known about its venom components, despite the fact that it can often cause human accidents. In this work, we performed a venomous gland transcriptome analysis by constructing and screening the venom gland cDNA library of the scorpion <it>Lychas mucronatus </it>from Yunnan province and compared it with the previous results of Hainan-sourced <it>Lychas mucronatus</it>.</p> <p>Results</p> <p>A total of sixteen known types of venom peptides and proteins are obtained from the venom gland cDNA library of Yunnan-sourced <it>Lychas mucronatus</it>, which greatly increase the number of currently reported scorpion venom peptides. Interestingly, we also identified nineteen atypical types of venom molecules seldom reported in scorpion species. Surprisingly, the comparative transcriptome analysis of Yunnan-sourced <it>Lychas mucronatus </it>and Hainan-sourced <it>Lychas mucronatus </it>indicated that enormous diversity and vastly abundant difference could be found in venom peptides and proteins between populations of the scorpion <it>Lychas mucronatus </it>from different geographical regions.</p> <p>Conclusions</p> <p>This work characterizes a large number of venom molecules never identified in scorpion species. This result provides a comparative analysis of venom transcriptomes of the scorpion <it>Lychas mucronatus </it>from different geographical regions, which thoroughly reveals the fact that the venom peptides and proteins of the same scorpion species from different geographical regions are highly diversified and scorpion evolves to adapt a new environment by altering the primary structure and abundance of venom peptides and proteins.</p
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